A post-doctoral position is available in the laboratory of Dr. Stephen Gomperts, Assistant Professor at the MassGeneral Institute for Neurodegenerative Disease (MIND) at Harvard Medical School, member of the Massachusetts Alzheimer’s Disease Research Center, and Director of the MGH Lewy Body Dementia Unit. The post-doctoral fellow will be working on characterizing and reversing the effects of Alzheimer’s disease on hippocampal function at the systems level, using a combination of electrophysiology, dynamic calcium imaging, optogenetic techniques, and pharmacological strategies in freely behaving mice.
The candidate will join an exciting, collaborative research environment at MIND and the Department of Neurology at Massachusetts General Hospital. The position offers exceptional training in electrophysiology, calcium imaging, Alzheimer’s disease, and molecular and non-molecular therapeutics.
Our lab studies how populations of neurons represent information, encode memories, and coordinate across brain regions in the service of behavior; and how to rescue the failure of these processes in disease. Specifically, we examine the contribution of neuromodulator systems to hippocampal physiology and of neuropathology cascades to hippocampal failure in Alzheimer’s, Parkinson’s, and related diseases using multi-electrode recording, dynamic calcium imaging, and opto/chemogenetics in freely behaving animals. We link these observations to our human imaging research to identify new insights and therapeutic strategies for these diseases.
Essential Qualifications: PhD in Neuroscience or a related area with specialization in electrophysiology or calcium imaging. Experience with freely-behaving preparations is preferred but not required.
Preferred Qualifications: The ideal candidate will be skilled in electrophysiology or dynamic calcium imaging, rodent experimentation, and data analysis techniques. Good verbal and written communication skills, the ability to work independently, and experience with Matlab or similar are a plus.
Additional Salary Information: Per NIH Salary Scale