We are seeking a motivated postdoctoral scholar to lead an NIH-funded project on Parkinson's disease mechanisms to begin on Jan. 2020.
Our lab aims to understand dopamine neuron and its nerve terminal function as well as their dysregulation in disease conditions. Loss of dopamine neurons in the substantia nigra leads to a debilitating neurodegenerative disorder - Parkinson's disease (PD). Evidence suggests that synaptic impairments may be an early sign of neurodegeneration. Our goal is to understand how synaptic PD-risk variants, such as SYNJ1 and SNCA, dysregulate synaptic function and ultimately give rise to specific vulnerability in the dopaminergic pathway. We use primary neuron cultures from genetic mouse models combined with quantitative imaging, biochemical and systems analyses to understand cell type specific regulation and vulnerability in PD pathogenesis.
The candidate is expected to have a PhD degree in Neuroscience or related field with a strong publication record, passion for scientific discovery, and prior experiences in 1) live cell imaging and/or synaptic physiology 2) primary neuronal cell culture and/or animal model, behavior, pathology.
A detail-oriented and quantitative mind is greatly appreciated. Additional expertise in molecular biology and biochemistry is desirable.
Applicants should submit a Curriculum Vitae, names of three references and a cover letter to email@example.com.
Internal Number: 19ST3004
About Rutgers University
Rutgers University offers tremendous training and career development opportunities for postdoctoral fellows. The university has a vibrant, collaborative neuroscience research community with over 250 research laboratories engaged in basic, translational and clinical neuroscience research. The Department of Neuroscience and Cell Biology is located on the Piscataway campus in central New Jersey with easy access to New York City and Philadelphia.
Dr. Pingyue Pan is a new Assistant Professor, who has initiated a series of exciting research programs currently supported by the institution, private foundations and NIH. The main research goal of the lab is to understand the dopaminergic synapse and its dysregulation in disease conditions. We are a small group, but we think big.